<< Return to News

Your Custom Microbial Fermentation Roadmap

When you partner with MDG for your custom fermentation needs, you can be confident that our microbiologists and production experts are committed to delivering a final culture that fits your specifications. We follow our Trusted Process closely, fostering success for our customers. But what does that process look like? Read on to discover what our custom microbial fermentation process entails, from pilot scale to commercialization.

Part One: Rapid Scale-Up

When you begin the custom fermentation process with MDG, your Bacillus strain will go through a process development program. This stage typically takes about twelve weeks to complete. The process development steps are as follows:

  1. MDG receives your strain in our in-house labs.
  2. Our microbiologists streak your strain to ensure purity.
  3. An initial growth screen begins, during which our specialists test your Bacillus strain’s growth ability on a multitude of different media.
  4. Growth media is narrowed down to a few top choices, and additional testing is performed to find the optimal media for your strain.
  5. Once we’ve found the right growth media, we will grow your strain on a pilot scale, harvest and dry the culture, and send it to you for evaluation.

After you give your approval on the final culture sample, the second part of the custom fermentation process can begin!

Part Two: Large-Scale Fermentation and Commercialization

Signing a contract with us and getting a spot on our fermentation schedule are the next steps when commercializing your strains with MDG. Depending on the volume needed, our team may start with small tanks or your strains might be scheduled for our 5,000 or 10,000 liter tanks right away. Our production facilities adhere to Good Manufacturing Practices (GMP) and are FSMA-compliant and HACCP-certified, so you know we take the necessary steps to ensure the quality and purity of your strain at every step of the process.

Once a tank is complete, our specialists harvest the culture and dry it, using either our spray dryers or freeze dryers. The result is a pure Bacillus culture in the form of a high-quality powder, ready to be used in your products and formulations.

Our Promises

MDG’s custom fermentation process encapsulates all three of the promises we make to each of our partners. In the lab, our microbiologists utilize Real Science during process development, finding the right media for your strain and optimizing growth conditions. Our production specialists follow a Trusted Process to ferment, harvest, and dry your strain. Finally, we see Proven Success in the commercialization process, getting you to scale efficiently and economically.

Interested in partnering with us for your custom fermentation needs? Contact us today and see how we can help you meet your unique goals and grow your business.

MDG is the Bacillus solution that helps you scale and streamline without sacrificing product effectiveness.

Search Insights
Recently Posted Insights

The Real Science of Custom Fermentation

Real Science, Trusted Process, Proven Success. These are the promises we make to each of our customers when they partner with MDG, and in custom fermentation, our focus on Real Science shines through. We’re experts in the precise, complex process of growing and...

Probiotic Market Trends and Challenges You Need to Know in 2025

The global probiotics market is anticipated to grow at an annual rate of 14% through 2030,1 which is exciting news for both new and established suppliers and manufacturers of probiotics. However, it’s hard to leverage this popularity without knowing about the...

Why Bacillus? A Closer Look at this Powerful Probiotic Ingredient

Lactobacillus and Bifidobacterium are two genera of vegetative bacteria whose historic success in probiotic applications has made them a common ingredient in many final products. However, Bacillus, a spore-forming bacteria, is becoming increasingly more popular due to...

Mitigate the Toughest Odors and Stains with SporActiv® CLEAR

When we formulate new industrial, institutional, and consumer (IIC) cleaning ingredients at MDG, your success is always top of mind. Our SporActiv® line includes scientifically proven products that can help you solve your customers’ challenges and reach your unique...

Biotifx® BLOCK: A Smarter Solution for Collection System Treatment

Collection systems are essential parts of the wastewater treatment process, and any operational interruptions can have a negative impact on their efficiency. Typical chemical and/or reactive treatments can also put a financial strain on system operators. Discover the...

BoostBac™ Probiotic: Access Our Exclusive White Paper!

At MDG, innovation is at the forefront of what we do. That’s why we’re thrilled to introduce our new probiotic ingredient—BoostBac™! BoostBac™ is a synergistically formulated dual-strain Bacillus probiotic clinically proven to reduce persistent systemic inflammation...

Trusted Process: MDG’s Gold Standard

MDG’s customer-centric approach to quality manufacturing and support ensures consistent, repeatable results for our customers. This is done through our trusted process; our gold standard at MDG. Can you be confident in our manufacturing process yielding consistent...

Defining Odors and Discovering Solutions with SporActiv®

In the industrial and institutional cleaning markets, odors are a major challenge, and you want to create effective solutions for your customers dealing with odor issues. This process can be daunting, however, as there are so many types of these unpleasant smells and...

Related News